Immunsil ® D3 Duo

Smart strengthening of the immune system

1 capsule contains:

  • β-glucan – 250 mg, containing 80% of β-1,3 and 1,6 links
  • Vitamin D3 – 4000 IU (100 mkg)
  • Zinс – 5 mg

Pack size:

  • 30, 60 capsules

Immunsil D3 Duo


  • Activates links of the artificial and innate immunity
  • Increases the number and activity of the innate immunity cells
  • Supports the immune function without overstimulating it
  • is a source of vitamin D3 and Zinc


  • To provide protection of the immune system during lingering seasonal respiratory infections
  • To decrease a risk of complications resulting from viral seasonal diseases
  • To fight deficit of vitamin D3 and Zinc
  • To be used in a combined therapy to treat immune response disorders
IMMUNSIL® D3 DUO – an innovative immune modulator with multifaceted activity

IMMUNSIL® D3 DUO is a first-ever composition uniting β-glucans, vitamin D3 and Zinc to offer long-term protection for the immune system yet avoid its excessive stimulation during unfavorable conditions, as well as compensate lack of vitamin D3 and Zinc.


  • Activate links of the artificial and innate immunity
  • Increase the number and activity level of neutrophils, macrophages, NK-cells
  • Shorten the duration of cold and flu
  • Prevent the onset of upper respiratory tract infections and reduce the severity of symptoms
  • Supports the immune function without stimulating the immune system excessively
  • Safe for long-term use
  • Have anti-inflammatory effect

Vitamin D3

  • Reduces the risk of respiratory infections and the severity of symptoms
  • Strengthens the links of innate immunity
  • Maintains the balance of calcium and phosphorus in the body
  • Boosts fertility and reproductive health
  • Improves psycho-emotional state, has antidepressant effect – an article informing about a relationship between the vitamin D3 level and complications from Covid-19 – the preliminary report of the study “The role of vitamin D in the prevention of coronavirus disease in 2019 and mortality” – “Most vulnerable population group in terms of COVID-19 is the one that has the greatest vitamin D deficiency” – vitamin D for prevention of acute respiratory tract infections: a systematic review and meta-analysis.


  • Modulates antiviral and antibacterial immunity
  • Possesses antiviral effect due to inhibition of RNA polymerase
  • It is required for the activity of more than 200 enzymes
  • Improves reproductive function in men
  • Promotes skin regeneration, hair and nail growth

IMMUNSIL® D3 DUO – is the best creation of nature for long-term protection of the immune system!

Direction for use of IMMUNSIL® D3 DUO

Ingredients: 1 capsule contains: active ingredients:
beta-glucan 250 mg, containing 80% of beta-glucans 1.3 and 1.6,
zinc 5 mg, the equivalent of zinc glycinate,
vitamin D3 (cholecalciferol) 100 µg (4,000 IU);
excipients: fillers: microcrystalline cellulose, lactose, calcium stearate, amorphous silicon dioxide (orisil); capsule shell: gelatin.

Nutritional and energy value (caloric value) per 100 g of the supplement: proteins 15.0 g, carbohydrates 1.1 g, fats 0 g; 64.4 kcal / 269.4 kJ.

Nutritional and energy value (caloric value) of daily amount, 2 capsules: proteins 0.13 g, carbohydrates 0.01 g, fats 0 g; 0.54 kcal / 2.26 kJ.

Recommendations for use: according to the physician’s recommendation, as an additional source of biologically active substances of plant origin, vitamin D and zinc in metabolic disorders caused by zinc and vitamin D deficiency, in order to normalize the functional state of the immune system, including during colds and infectious diseases. IMMUNSIL® D3 DUO has immunomodulatory properties and contributes to the inhibition of the development of viruses and bacteria through the activation of local and systemic immunity. IMMUNSIL® D3 DUO reduces the risk of viral and respiratory diseases during peak seasonal infections, prevents complications, and promotes faster recovery. IMMUNSIL® D3 DUO compensates for the lack of zinc and vitamin D in the body and has a positive effect on metabolism.

How to use and recommended daily dose: adults with normal body weight and elderly people should take 1 capsule per day during seasonal viral infections and/or vitamin D and zinc deficiency; adults with obesity and elderly people with obesity should take 2 capsules per day to accelerate recovery and prevent the development of complications during seasonal viral infections. IMMUNSIL® D3 DUO should be taken during meals, while washing down with enough drinking water.

Recommended intake course: 1-3 months. If necessary, the course can be repeated upon the physician’s recommendation.

Consult a physician before use.

Contraindications: individual intolerance to components, including lactose, paediatric use, pregnancy and lactation, severe kidney disease, hypermagnesemia, hypercalciuria, and hypervitaminosis D.

Special warnings and precautions for use: IMMUNSIL® D3 DUO may be used only 2 hours after the use of tetracycline and iron-containing medicinal products. It is not recommended to use concomitantly with laxatives and cardiac glycosides.

Do not exceed the specified recommended amount for daily intake.

Do not use it as a substitute for a complete diet.

Dosage form: capsules with a content of 350 mg ± 7.5%.

Storage conditions: Store in the original packaging in a dry place, protected from sunlight and out of reach of children, at a temperature from 4 °C to 25 °C.

Shelf life: 24 months from the date of manufacture.

Additional information

Beta-glucans (β-glucans) are a group of polysaccharides consisting of D-glucose monomers and are structural elements of the membrane of Saccharomyces cerevisiae yeast fungi. Numerous studies have proven that beta-glucans (1.3 and 1.6) are potent natural immunomodulators. The main mechanism of action of beta-glucans is direct interaction with macrophage receptors, which activates non-specific protective mechanisms and the development of a specific immune response: activation of cytotoxic macrophages, increased production of interleukin 1 by macrophages, stimulation of T-lymphocytes, increased production of other cytokines, activation of killer cells (NK cells), increased levels of acute phase protein in serum.

Beta-glucans have anti-inflammatory properties (inhibit the synthesis of pro-inflammatory cytokines: interleukins 6 and 12) and enhance the synthesis of interferon. Thus, beta-glucans activate both local immunity, providing the first line of protection of the human body against microorganisms, and systemic immunity, which leads to the destruction of pathogens when they enter the body. Enhancement of immunity by beta-glucans (1.3 and 1.6) occurs without its excessive stimulation, which prevents autoimmune disorders. Beta-glucans also have a positive effect on lipid metabolism, lowering blood cholesterol and glucose levels, have antioxidant properties and contribute to the normalization of intestinal microbiome.

Vitamin D3 (cholecalciferol) is one of the key vitamins involved in the functioning of the immune system, affecting the synthesis of lymphokines, substances produced by lymphocytes, thereby ensuring the flow of immune reactions.
Vitamin D3 is involved in other processes of metabolism in the body, and also performs various functions in the human body: contributes to preservation of the normal state of the bones, contributes to the normal functioning of muscles, contributes to the normal absorption/consumption of calcium and phosphorus, contributes to the normalization of calcium in the blood, contributes to the normal state of teeth, and participates in cell division.

Zinc is one of the most important micronutrients that is part of many enzyme systems that regulate the basic processes of metabolism, namely: it is involved in the synthesis of proteins and in the metabolism of carbohydrates. Zinc contributes to the growth and development of cells, the correct functioning of the immune system and the provision of an immunological response, ambiguous vision, taste and perception of smell. It affects the preservation of normal levels of vitamin A in the blood, prolongs the time of action of insulin and facilitates its accumulation.

Zinc contributes to the improvement of male reproductive function, which is necessary for the formation of normal sperm. Zinc is necessary for normal skin function, is involved in the processes of skin regeneration, sebaceous gland secretion, nail and hair growth.