{"id":7560,"date":"2021-01-21T09:08:10","date_gmt":"2021-01-21T06:08:10","guid":{"rendered":"https:\/\/nutrimed.ua\/our-products\/deprilium\/"},"modified":"2025-08-19T17:24:02","modified_gmt":"2025-08-19T14:24:02","slug":"deprilium","status":"publish","type":"page","link":"https:\/\/nutrimed.ua\/en\/our-products\/deprilium\/","title":{"rendered":"DEPRILIUM"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: left top;background-repeat: no-repeat;padding-top:20px;padding-right:0px;padding-bottom:20px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last fusion-column-no-min-height\" style=\"margin-top:0px;margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-one\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h1 class=\"title-heading-center\" style=\"margin:0;\"><span class=\"deprilium_title\">Deprilium<sup>\u00ae<\/sup><\/span><\/h1><\/div><style type=\"text\/css\"><\/style><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"margin-top:0px;margin-right:0px;margin-bottom:31px;margin-left:0px;\"><h2 class=\"title-heading-center\" style=\"margin:0;\"><span class=\"deprilium_title\">Natural improvement of psycho-emotional state<\/span><\/h2><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: left top;background-repeat: no-repeat;padding-top:20px;padding-right:0px;padding-bottom:20px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:20px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-tabs fusion-tabs-1 clean vertical-tabs icon-position-left\"><style type=\"text\/css\">#wrapper .fusion-tabs.fusion-tabs-1.clean .nav-tabs li a.tab-link{border-color:#ebeaea;}.fusion-tabs.fusion-tabs-1 .nav-tabs li a.tab-link{background-color:#ebeaea;}.fusion-tabs.fusion-tabs-1 .nav-tabs li.active a.tab-link,.fusion-tabs.fusion-tabs-1 .nav-tabs li.active a.tab-link:hover,.fusion-tabs.fusion-tabs-1 .nav-tabs li.active a.tab-link:focus{background-color:#ffffff;}.fusion-tabs.fusion-tabs-1 .nav-tabs li a:hover{background-color:#ffffff;border-top-color:#ffffff;}.fusion-tabs.fusion-tabs-1 .tab-pane{background-color:#ffffff;}.fusion-tabs.fusion-tabs-1 .nav,.fusion-tabs.fusion-tabs-1 .nav-tabs,.fusion-tabs.fusion-tabs-1 .tab-content .tab-pane{border-color:#ebeaea;}<\/style><div class=\"nav\"><ul class=\"nav-tabs\" role=\"tablist\"><li class=\"active\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-920a290beaa184c3731\" aria-selected=\"true\" id=\"fusion-tab-composition\" href=\"#tab-920a290beaa184c3731\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-th-list fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Composition<\/h4><\/a><\/li><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-45f05bf9b72b3ee81ea\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-therapeuticeffects\" href=\"#tab-45f05bf9b72b3ee81ea\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-check-square far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Therapeutic effects<\/h4><\/a><\/li><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3e0f3ee2add301c8a70\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-description\" href=\"#tab-3e0f3ee2add301c8a70\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-file-alt far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Description<\/h4><\/a><\/li><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-4b821e27efbe620039a\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-directionforuse\" href=\"#tab-4b821e27efbe620039a\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-edit far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Direction for use<\/h4><\/a><\/li><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5992ccfc6a1381bc078\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-clinicalstudiesandarticles\" href=\"#tab-5992ccfc6a1381bc078\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-info-circle fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Clinical studies and articles<\/h4><\/a><\/li><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-f0084314dd0cf58916a\" aria-selected=\"false\" tabindex=\"-1\" id=\"fusion-tab-wheretobuy\" href=\"#tab-f0084314dd0cf58916a\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-shopping-basket fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Where to buy<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-content\"><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li class=\"active\"><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-920a290beaa184c3731\" aria-selected=\"true\" id=\"mobile-fusion-tab-composition\" href=\"#tab-920a290beaa184c3731\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-th-list fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Composition<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix in active\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-composition\" id=\"tab-920a290beaa184c3731\"><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-0 fusion_builder_column_inner_3_5 3_5 fusion-three-fifth fusion-column-first\" style=\"width:60%;width:calc(60% - ( ( 4% ) * 0.6 ) );margin-right: 4%;margin-top:0px;margin-bottom:20px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\">\n<div class=\"fusion-text fusion-text-1\"><h4>1 capsule contains:<\/h4>\n<\/div>\n<ul class=\"fusion-checklist fusion-checklist-1\" style=\"font-size:13px;line-height:22.1px;\">\n<li class=\"fusion-li-item\"><span style=\"height:22.1px;width:22.1px;margin-right:9.1px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-leaf\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:31.2px;\">S-adenosyl-L-methionine \u2013 200 mg<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:22.1px;width:22.1px;margin-right:9.1px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-leaf\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:31.2px;\">L- methylfolate \u2013 0,4 mg, equivalent to 0,4 mg of folic acid<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:22.1px;width:22.1px;margin-right:9.1px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-leaf\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:31.2px;\">Vitamin B12 as methylcobalamin \u2013 250 \u00b5g<\/div><\/li>\n<\/ul>\n<div class=\"fusion-text fusion-text-2\"><h4>Pack size:<\/h4>\n<\/div>\n<ul class=\"fusion-checklist fusion-checklist-2\" style=\"font-size:13px;line-height:22.1px;\">\n<li class=\"fusion-li-item\"><span style=\"height:22.1px;width:22.1px;margin-right:9.1px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-cube\" style=\"color:#8d8e8e;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:31.2px;\">\n<h4>30 capsules<\/h4>\n<\/div><\/li>\n<\/ul>\n<div class=\"fusion-clearfix\"><\/div><\/div><\/div>\n<div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-1 fusion_builder_column_inner_2_5 2_5 fusion-two-fifth fusion-column-last\" style=\"width:40%;width:calc(40% - ( ( 4% ) * 0.4 ) );margin-top:0px;margin-bottom:20px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\">\n<div class=\"imageframe-align-center\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-zoomin\"><img width=\"700\" height=\"825\" alt=\"Deprilium\" title=\"DEPRILIUM_30_caps_new_2024\" src=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/2024\/08\/DEPRILIUM_30_caps_new_2024.png\" class=\"img-responsive wp-image-8684\" srcset=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/2024\/08\/DEPRILIUM_30_caps_new_2024-200x236.png 200w, https:\/\/nutrimed.ua\/wp-content\/uploads\/2024\/08\/DEPRILIUM_30_caps_new_2024-400x471.png 400w, https:\/\/nutrimed.ua\/wp-content\/uploads\/2024\/08\/DEPRILIUM_30_caps_new_2024-600x707.png 600w, https:\/\/nutrimed.ua\/wp-content\/uploads\/2024\/08\/DEPRILIUM_30_caps_new_2024.png 700w\" sizes=\"(max-width: 800px) 100vw, 600px\" \/><\/span><\/div>\n<div class=\"fusion-clearfix\"><\/div><\/div><\/div>\n<\/div><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-45f05bf9b72b3ee81ea\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-therapeuticeffects\" href=\"#tab-45f05bf9b72b3ee81ea\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-check-square far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Therapeutic effects<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-therapeuticeffects\" id=\"tab-45f05bf9b72b3ee81ea\">\n<h3>DEPRILIUM<sup>\u00ae<\/sup>:<\/h3>\n<ul class=\"fusion-checklist fusion-checklist-3\" style=\"font-size:14px;line-height:23.8px;\">\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-check-square-o\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Has a moderate antidepressant effect<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-check-square-o\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Regulates the metabolism of neurotransmitters<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-check-square-o\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Improves cognitive function and performance<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-check-square-o\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Demonstrates neuroprotective properties<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-check-square-o\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Has a good safety profile<\/div><\/li>\n<\/ul>\n<h4>Recommendations for use:<\/h4>\n<p>Depressive syndrome associated with<ul class=\"fusion-checklist fusion-checklist-4\" style=\"font-size:14px;line-height:23.8px;\">\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-hand-o-right\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Depressed mood<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-hand-o-right\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Apathy<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-hand-o-right\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Easy fatigability<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-hand-o-right\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Low self-esteem<\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-hand-o-right\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">Decreased working ability and cognitive function<\/div><\/li>\n<\/ul><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-3e0f3ee2add301c8a70\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-description\" href=\"#tab-3e0f3ee2add301c8a70\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-file-alt far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Description<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-description\" id=\"tab-3e0f3ee2add301c8a70\"><strong>DEPRILIUM<sup>\u00ae<\/sup><\/strong> is an innovative natural complex for depressive disorders. Efficacy of <strong>DEPRILIUM<sup>\u00ae<\/sup><\/strong> components use in clinical trials. <strong>DEPRILIUM<sup>\u00ae<\/sup><\/strong> components have a long-term history of use in the USA and EU.<\/p>\n<p><strong>DEPRILIUM<sup>\u00ae<\/sup><\/strong> contains a scientifically proven combination of natural substances that normalizes the psycho-emotional state by improving the metabolism of neurotransmitters in the brain resulting in the relief of such manifestations as depressed mood, apathy, easy fatigability, low self-esteem, etc.; improved mood and well-being; increased working ability and concentration; improved cognitive functions.<\/p>\n<p><strong><em>S-adenosyl-L-methionine, SAMe,<\/em><\/strong> is a natural substance found in all cells of the body that is involved in more than 200 metabolic processes. Numerous clinical studies with S-adenosyl-L-methionine have proven its efficacy in depressive syndrome. S-adenosyl-L-methionine is characterized by a rapid physiological effect and favorable safety profile. S-adenosyl-L-methionine crosses the blood-brain barrier and is involved in the synthesis of CNS neurotransmitters (including serotonin, catecholamines, melatonin, and histamine).<\/p>\n<p><strong><em>L-methylfolate <\/em><\/strong> is a biologically active form of folic acid (vitamin B9). Based on several studies, depression is associated with a decreased serum folate level. L-methylfolate requires no additional transformations in the body and is the only form of folic acid that crosses the blood-brain barrier. Methylfolate plays an important role in the synthesis of major CNS neurotransmitters. L-methylfolate helps relieve the manifestations of depressive syndrome.<\/p>\n<p><strong><em>Methylcobalamin<\/em><\/strong> is one of the active forms of Vitamin B12. Methylcobalamin, at the subcellular level, is much better transported to the organelles of the nerve cells. Because of this feature, it is more effective in improving the psycho-emotional state and normalizing nervous system functioning. People with depressive syndrome have been reported to have a low level of Vitamin B12. Its metabolism is strongly related to folate and SAMe.<\/p>\n<p style=\"text-align: center;\"><span class=\"deprilium_title\">DEPRILIUM<sup>\u00ae<\/sup> contains a scientifically proven combination of natural substances that normalizes the psycho-emotional state by improving the metabolism of neurotransmitters in the brain<\/span><\/p>\n<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-4b821e27efbe620039a\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-directionforuse\" href=\"#tab-4b821e27efbe620039a\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-edit far\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Direction for use<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-directionforuse\" id=\"tab-4b821e27efbe620039a\"><ul class=\"fusion-checklist fusion-checklist-5\" style=\"font-size:14px;line-height:23.8px;\">\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"Direction for use in PDF format\" href=\"https:\/\/www.nutrimed.ua\/wp-content\/uploads\/instructions\/DEPRILIUM_instruction_EN.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Direction for use in PDF format<\/a><\/div><\/li>\n<\/ul>\n<p><strong>Direction for use of Deprilium\u00ae<\/strong><\/p>\n<p><strong>Ingredients:<\/strong> 1 capsule contains: active ingredients:<br \/>\n<strong>S-adenosyl-L-methionine 200 mg,<\/strong><br \/>\n<strong>L-methylfolate 0.4 mg, equivalent to 0.4 mg of folic acid,<\/strong><br \/>\n<strong>vitamin B12 in the form of methylcobalamin 250 \u00b5g; <\/strong><br \/>\n<em>excipients: fillers:<\/em> microcrystalline cellulose, calcium stearate, amorphous silicon dioxide (orisil); <em>capsule shell:<\/em> gelatin.<\/p>\n<p><strong>Nutritional and energy value (caloric value) per 100 g of dietary supplement:<\/strong> proteins 15.0 g, carbohydrates 1.1 g, fats 0 g; 64.4 kcal \/ 269.4 kJ.<\/p>\n<p><strong>Nutritional and energy value (caloric value) of daily amount, 2 capsules:<\/strong> proteins 0.13 g, carbohydrates 0.01 g, fats 0 g; 0.54 kcal \/ 2.26 kJ.<\/p>\n<p><strong>Recommendations for use:<\/strong> <strong>DEPRILIUM\u00ae<\/strong> is recommended as an additional source of amino acids and vitamins for normalizing the functioning of the nervous system in depressed psychoemotional state, apathy, reduced concentration of attention and performance associated with impaired metabolism of central neurotransmitters (serotonin, noradrenaline, etc.) <strong>DEPRILIUM\u00ae<\/strong> has neuroprotective properties, improves mood and well-being, increases cognitive functions and performance. <strong>DEPRILIUM\u00ae<\/strong> compensates for the deficiency of folic acid and vitamin B12 in the body, which contributes to the normalization of the psychoemotional state.<\/p>\n<p><strong>How to use and recommended daily dose:<\/strong> adults should take 1-2 capsules a day 30 minutes before or 1 hour after meals (but not later than 16 hours), while washing down with enough drinking water.<\/p>\n<p><strong>Recommended intake course:<\/strong> 1-3 months. If necessary, the intake course can be adjusted by a physician.<\/p>\n<p><strong>Consult your physician before use.<\/strong><\/p>\n<p><strong>Do not exceed the specified recommended amount for daily intake.<\/strong><\/p>\n<p><strong>Do not use it as a substitute for a complete diet.<\/strong><\/p>\n<p><strong>Contraindications:<\/strong> pregnancy, lactation period, paediatric use, individual intolerance to components, bipolar disorders, malignant neoplasms, blood system diseases.<\/p>\n<p><strong>Dosage form:<\/strong> capsules with a content of 340 mg \u00b1 7.5%.<\/p>\n<p><strong>Storage conditions:<\/strong> store in the original packaging in a dry place, protected from sunlight and out of reach of children, at a temperature from 4 \u00b0C to 25 \u00b0C.<\/p>\n<p><strong>Date of manufacture:<\/strong> the date of manufacture is indicated on the package.<\/p>\n<p><strong>Shelf life:<\/strong> 24 months from the date of manufacture.<\/p>\n<p><strong>Production batch number:<\/strong> indicated on the package.<br \/>\n<strong><br \/>\nAdditional information<\/strong><\/p>\n<p><strong>DEPRILIUM\u00ae <\/strong>contains a scientifically based combination of substances of natural origin for the normalization of the psycho-emotional state, by improving the metabolism of neurotransmitters in the brain, which leads to: a decrease in such manifestations as depressed mood, apathy, rapid fatigue, decreased self-esteem, etc.; improved mood and well-being; increased performance and concentration of attention; improved cognitive functions.<\/p>\n<p><em>S-adenosyl-L-methionine (SAMe)<\/em> is a substance of natural origin that is present in all cells of the body and is involved in more than 200 metabolic processes. SAMe has a long history of use, including in the European Union and the United States. Numerous clinical studies of S-adenosyl-L-methionine have proven its effectiveness in depressive syndrome. S-adenosyl-L-methionine is characterized by a high rate of onset of physiological effect and a favourable safety profile. S-adenosyl-L-methionine penetrates through the blood-brain barrier, where it is involved in the synthesis of CNS neurotransmitters (in particular serotonin, catecholamines, melatonin, histamine).<\/p>\n<p><em>L -methylfolate <\/em>is a biologically active form of folic acid (vitamin B9), which is an important nutrient and is mainly contained in green leaves and vegetables. Folic acid is easily destroyed in the preparation and processing of food; its level in the body is affected by many factors. According to a number of studies, a decrease in serum folate levels is observed in depressions. L-methylfolate does not require additional transformation in the body and is the only form of folic acid that penetrates the blood-brain barrier. Methylfolate plays an important role in the synthesis of major CNS neurotransmitters, amino acids, proteins, and nucleic acids. L-methylfolate contributes to reducing the manifestations of depressive syndrome.<\/p>\n<p><em>Methylcobalamin<\/em> is one of the active forms of vitamin B12. Compared to other forms of vitamin B12, methylcobalamin at the subcellular level is better transported into the neuronal organelles. Due to this property, it is more effective for improving the psycho-emotional state and normalizing the functioning of the nervous system. Low levels of vitamin B12 are observed in people with depressive syndrome. Its metabolism is closely related to folate and SAMe; methylcobalamin plays an important role in the metabolism of neurotransmitters. Vitamin B12 is involved in cell division and blood formation, and is crucial for the normal functioning of nerve tissue. Methylcobalamin is responsible for the regeneration and new formation of nerve fibre membranes (also known as myelin membranes) that protect the nerves and ensure the correct and effective transmission of nerve impulse.<\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-5992ccfc6a1381bc078\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-clinicalstudiesandarticles\" href=\"#tab-5992ccfc6a1381bc078\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-info-circle fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Clinical studies and articles<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-clinicalstudiesandarticles\" id=\"tab-5992ccfc6a1381bc078\"><ul class=\"fusion-checklist fusion-checklist-6\" style=\"font-size:14px;line-height:23.8px;\">\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"\u041a\u043b\u0456\u043d\u0456\u0447\u043d\u0456 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0442\u0430 \u0441\u0442\u0430\u0442\u0442\u0456 \u0414\u0435\u043f\u0440\u0456\u043b\u0456\u0443\u043c\" href=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/publications\/deprilium\/Neuro_1_2021_burchinkskiy.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u0414\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u044f \u0438 \u0442\u0440\u0435\u0432\u043e\u0433\u0430 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u043f\u043e\u0441\u043b\u0435 \u043f\u0435\u0440\u0435\u043d\u0435\u0441\u0435\u043d\u043d\u043e\u0433\u043e COVID-19: \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e\u0441\u0442\u0438 \u043a\u043e\u043c\u0431\u0438\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438. \u0421.\u0413. \u0411\u0443\u0440\u0447\u0438\u043d\u0441\u043a\u0438\u0439<\/a><\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"\u041a\u043b\u0456\u043d\u0456\u0447\u043d\u0456 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0442\u0430 \u0441\u0442\u0430\u0442\u0442\u0456 \u0414\u0435\u043f\u0440\u0456\u043b\u0456\u0443\u043c\" href=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/publications\/deprilium\/UMJ_deprilium_burchinskiy.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u041d\u0435\u0439\u0440\u043e\u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0456\u0447\u043d\u0430 \u0441\u0442\u0440\u0430\u0442\u0435\u0433\u0456\u044f \u0444\u0430\u0440\u043c\u0430\u043a\u043e\u0442\u0435\u0440\u0430\u043f\u0456\u0457 \u0430\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0438\u0445 \u0440\u043e\u0437\u043b\u0430\u0434\u0456\u0432: \u043a\u043e\u043c\u0443, \u043a\u043e\u043b\u0438 \u0456 \u043d\u0430\u0432\u0456\u0449\u043e? \u0421.\u0413. \u0411\u0443\u0440\u0447\u0438\u043d\u0441\u044c\u043a\u0438\u0439<\/a><\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"\u041a\u043b\u0456\u043d\u0456\u0447\u043d\u0456 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0442\u0430 \u0441\u0442\u0430\u0442\u0442\u0456 \u0414\u0435\u043f\u0440\u0456\u043b\u0456\u0443\u043c\" href=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/publications\/deprilium\/neuronews_deprilium_cerebrovital.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u0414\u0435\u043f\u0440\u0435\u0441\u0456\u0457 \u0442\u0430 \u043a\u043e\u0433\u043d\u0456\u0442\u0438\u0432\u043d\u0456 \u043f\u043e\u0440\u0443\u0448\u0435\u043d\u043d\u044f: \u043c\u043e\u0436\u043b\u0438\u0432\u043e\u0441\u0442\u0456 \u043a\u043e\u043c\u0431\u0456\u043d\u043e\u0432\u0430\u043d\u043e\u0457 \u0442\u0435\u0440\u0430\u043f\u0456\u0457. \u0421. \u0413. \u0411\u0443\u0440\u0447\u0438\u043d\u0441\u044c\u043a\u0438\u0439, \u041d. \u042e. \u0411\u0430\u0447\u0438\u043d\u0441\u044c\u043a\u0430<\/a><\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"\u041a\u043b\u0456\u043d\u0456\u0447\u043d\u0456 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0442\u0430 \u0441\u0442\u0430\u0442\u0442\u0456 \u0414\u0435\u043f\u0440\u0456\u043b\u0456\u0443\u043c\" href=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/publications\/deprilium\/problemy_bezpeky_farmakoterapii_deprilium.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u041f\u0440\u043e\u0431\u043b\u0435\u043c\u0430 \u0431\u0435\u0437\u043f\u0435\u043a\u0438 \u0444\u0430\u0440\u043c\u0430\u043a\u043e\u0442\u0435\u0440\u0430\u043f\u0456\u0457 \u0430\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0438\u0445 \u0440\u043e\u0437\u043b\u0430\u0434\u0456\u0432: \u043d\u043e\u0432\u0456 \u043c\u043e\u0436\u043b\u0438\u0432\u043e\u0441\u0442\u0456. \u0421. \u0413. \u0411\u0443\u0440\u0447\u0438\u043d\u0441\u044c\u043a\u0438\u0439<\/a><\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-info-circle\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\"><a title=\"\u041a\u043b\u0456\u043d\u0456\u0447\u043d\u0456 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0442\u0430 \u0441\u0442\u0430\u0442\u0442\u0456 \u0414\u0435\u043f\u0440\u0456\u043b\u0456\u0443\u043c\" href=\"https:\/\/nutrimed.ua\/wp-content\/uploads\/publications\/deprilium\/DEPRILIUM_international_article_01_2023.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Safety and efficacy of the complex Deprilium\u00ae in reducing subclinical symptoms of depression in patients with chronic non-communicable diseases: double-blind randomized controlled study. \u041eleg S. Chaban, Olena O. Khaustova, Dmytro O. Assonov, Lesia V. Sak<\/a><\/div><\/li>\n<\/ul><\/div><div class=\"nav fusion-mobile-tab-nav\"><ul class=\"nav-tabs\"><li><a class=\"tab-link\" data-toggle=\"tab\" role=\"tab\" aria-controls=\"tab-f0084314dd0cf58916a\" aria-selected=\"false\" tabindex=\"-1\" id=\"mobile-fusion-tab-wheretobuy\" href=\"#tab-f0084314dd0cf58916a\"><h4 class=\"fusion-tab-heading\"><i class=\"fontawesome-icon fa-shopping-basket fas\" aria-hidden=\"true\" style=\"font-size:13px;\"><\/i>Where to buy<\/h4><\/a><\/li><\/ul><\/div><div class=\"tab-pane fade fusion-clearfix\" role=\"tabpanel\" tabindex=\"0\" aria-labelledby=\"fusion-tab-wheretobuy\" id=\"tab-f0084314dd0cf58916a\"><ul class=\"fusion-checklist fusion-checklist-7\" style=\"font-size:14px;line-height:23.8px;\">\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa fa-plus-square\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">At Ukrainian pharmacies:<br \/>\n<a title=\"Where to buy Deprilium\" href=\"https:\/\/tabletki.ua\/uk\/%D0%94%D0%B5%D0%BF%D1%80%D0%B8%D0%BB%D0%B8%D1%83%D0%BC\/1036066\/\" target=\"_blank\" rel=\"noopener noreferrer\">click the link and select a city \/ district \u00bb<\/a><\/div><\/li>\n<li class=\"fusion-li-item\"><span style=\"height:23.8px;width:23.8px;margin-right:9.8px;\" class=\"icon-wrapper circle-no\"><i class=\"fusion-li-icon fa-cart-plus fas\" style=\"color:#008d82;\" aria-hidden=\"true\"><\/i><\/span><div class=\"fusion-li-item-content\" style=\"margin-left:33.6px;\">\n<div class=\"fusion-text fusion-text-3\"><p>In the internet-shop of our company<\/p>\n<\/div><div class=\"fusion-alignleft\"><style type=\"text\/css\">.fusion-button.button-1 {border-radius:2px;}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" title=\"Go to Internet Shop\" href=\"https:\/\/nutrimed-shop.com\/product\/deprilium\/\"><span class=\"fusion-button-icon-divider button-icon-divider-left\"><i class=\"fa-cart-plus fas\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-button-text fusion-button-text-left\">Buy Deprilium<\/span><\/a><\/div>\n<\/div><\/li>\n<\/ul><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":441,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/pages\/7560"}],"collection":[{"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/comments?post=7560"}],"version-history":[{"count":12,"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/pages\/7560\/revisions"}],"predecessor-version":[{"id":8971,"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/pages\/7560\/revisions\/8971"}],"up":[{"embeddable":true,"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/pages\/441"}],"wp:attachment":[{"href":"https:\/\/nutrimed.ua\/en\/wp-json\/wp\/v2\/media?parent=7560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}